Peer-Reviewed Journal Articles(*Corresponding author; #Co-first author)

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2022

Shi M, Yu L, Shi J, Liu J* (2022) A conserved MYB transcription factor is involved in regulating lipid metabolic pathways for oil biosynthesis in green algae. New Phytologist, 235: 576-594

Yang J#, Liu J#, Pan Y, Marechal E, Amato A, Liu M, Gong Y, Li Y, Hu H* (2022) PDAT regulates PE as transient carbon sink alternative to triacylglycerol in Nannochloropsis. Plant Physiology, 189: 1345–1362

Bai F, Yu L, Shi J, Li-Beisson Y, Liu J* (2022) Long-chain acyl-CoA synthetases activate fatty acids for lipid synthesis, remodeling and energy production in Chlamydomonas. New Phytologist, 233: 823-837

Liu J*, Liu M, Pan Y, Shi Y, Hu H (2022) Metabolic engineering of the oleaginous alga Nannochloropsis for enriching eicosapentaenoic acid in triacylglycerol by combined pulling and pushing strategies. Metabolic Engineering, 69: 163-174

2021

Wu T, Yu L, Zhang Y, Liu J* (2021) Characterization of fatty acid desaturases reveals stress-induced synthesis of C18 unsaturated fatty acids enriched in triacylglycerol in the oleaginous alga Chromochloris zofingiensis. Biotechnology for Biofuels, 14:184.

Shi Y, Liu M, Pan Y, Hu H, Liu J* (2021) Δ6 Fatty Acid Elongase is Involved in Eicosapentaenoic Acid Biosynthesis Via the ω6 Pathway in the Marine Alga Nannochloropsis oceanica. Journal of Agricultural and Food Chemistry, 69:9837−9848. 

Bai F, Zhang Y, Liu J* (2021) A bZIP transcription factor is involved in regulating lipid and pigment metabolisms in the green alga Chlamydomonas reinhardtii. Algal Research 59:102450. 

Zhang Y, Ye Y, Bai F, Liu J* (2021) The oleaginous astaxanthin-producing alga Chromochloris zofingiensis: potential from production to an emerging model for studying lipid metabolism and carotenogenesis. Biotechnology for Biofuels 14: 119.

Zhang Y#, Pan Y#, Ding W, Hu H, Liu J* (2021) Lipid production is more than doubled by manipulating a diacylglycerol acyltransferase in algae. GCB Bioenergy, 13: 185–200

2020

Shi Y, Liu M, Ding W, Liu J* (2020) Novel insights into phosphorus deprivation-boosted lipid synthesis in the marine alga Nannochloropsis oceanica without compromising biomass production. Journal of Agricultural and Food Chemistry, 68: 11488–11502.

Zhang Y, Ye Y, Ding W, Mao X, Li Y, Gerken H, Liu J* (2020). Astaxanthin is ketolated from zeaxanthin independent of fatty acid synthesis in Chromochloris zofingiensis. Plant Physiology 183: 883-897

Kou Y, Liu M, Sun P, Dong Z, Liu J* (2020) High light boosts salinity stress-induced biosynthesis of astaxanthin and lipids in the green alga Chromochloris zofingiensis. Algal Research 50: 101976

Mao X#, Zhang Y#, Wang X#, Liu J* (2020) Novel insights into salinity-induced lipogenesis and carotenogenesis in the oleaginous astaxanthin-producing alga Chromochloris zofingiensis: a multi-omics study. Biotechnology for Biofuels,13: 73

Wu T, Fu Y, Shi Y, Li Y, Kou Y, Mao X, Liu J* (2020) Functional Characterization of Long-Chain Acyl-CoA Synthetase Gene Family from the Oleaginous Alga Chromochloris zofingiensis. Journal of Agricultural and Food Chemistry, 68: 4473-4484

2019

Zhang Y, Shi M, Mao X, Kou Y, Liu J* (2019) Time-resolved carotenoid profiling and transcriptomic analysis reveal mechanism of carotenogenesis for astaxanthin synthesis in the oleaginous green alga Chromochloris zofingiensis. Biotechnology for Biofuels, 12:287

Sun Z, Wang X, Liu J* (2019) Screening of Isochrysis strains for simultaneous production of docosahexaenoic acid and fucoxanthin. Algal Research, 41: 101545

Wang X, Wei H, Mao X, Liu J* (2019) Proteomics analysis of lipid droplets from the oleaginous alga Chromochloris zofingiensis reveals novel proteins for lipid metabolism. Genomics, Proteomics & Bioinformatics, 17: 260-272

Sun Z, Zhang Y, Sun L-p, Liu J* (2019) Light Elicits Astaxanthin Biosynthesis and Accumulation in the Fermented Ultrahigh-Density Chlorella zofinginesis. Journal of Agricultural and Food Chemistry, 67: 5579–5586

Liu J*, Sun Z, Mao X, Gerken H, Wang X, Yang W (2019) Multi-omics analysis reveals distinct mechanism of oleaginousness in the emerging model alga Chromochloris zofingiensis. Plant Journal, 2019;98:1060–1077

Mao X, Wu T, Kou Y, Shi Y, Zhang Y, Liu J* (2019) Characterization of type I and II diacylglycerol acyltransferases from the emerging model alga Chlorella zofingiensis reveals their functional complementarity and engineering potential. Biotechnology for Biofuels, 12: 28

Shi M, Wei H, Chen Q, Wang X, Zhou W, Liu J* (2019) Exploring an isolate of the oleaginous alga Micractinium inermum for lipid production: molecular characterization and physiochemical analysis under multiple growth conditions. Journal of Applied Phycology, 31, 1035-1046

Cheng K, Xu Y, Yang C, Ouellette L, Niu L, Zhou X, Chu L, Zhuang F, Liu J, Wu H, Charron JB, Luo M (2019) Histone tales: lysine methylation, a protagonist in Arabidopsis development. Journal of Experimental Botany, 71: 793-807

2018

Sun Z, Wei H, Zhou Z-g, Ashokkumar M, Liu J* (2018) Screening of Isochrysis Strains and Utilization of a Two-Stage Outdoor Cultivation Strategy for Algal Biomass and Lipid Production. Applied Biochemistry and Biotechnology, 185: 1100–1117

Chen J, Leng L, Ye C, Lu Q, Addy M, Wang J, Liu J, Chen P, Ruan R, Zhou W (2018) A comparative study between fungal pellet- and spore-assisted microalgae harvesting methods for algae bioflocculation. Bioresource Technology, 259: 181-190

Yang C, Shen W, Chen H, Chu L, Xu Y, Zhou X, Liu C, Chen C, Zeng J, Liu J, Li Q, Gao C, Charron J-B, Luo M (2018) Characterization and subcellular localization of histone deacetylases and their roles in response to abiotic stresses in soybean. BMC Plant Biology 18: 226

Ma X, Liu B, Yang B, Guo B, Liu J*, Chen F* (2018) Physiochemical and gene expression analyses reveal differential responses of the marine oleaginous alga Nannochloropsis salina under different lipid-induction conditions. Journal of Applied Phycology, 30: 909-919

2017

Xin Y#, Lu Y#, Lee Y#, Wei L, Jia J, Wang Q, Wang D, Bai F, Hu H, Hu Q, Liu J*, Li Y*, Xu J* (2017) Producing designer oils in industrial microalgae by rational modulation of co-evolving type-2 diacylglycerol acyltransferases. Molecular Plant, 10: 1523-1539

Sun Z, Chen Y, Mao X, Liu J* (2017) Physiological and biochemical changes reveal differential patterns of docosahexaenoic acid partitioning in two marine algal strains of Isochrysis. Marine Drugs, 15: 357

Wei HH, Shi Y, Ma XN, Pan Y, Hu HH, Li YT, Luo M, Gerken H, Liu J* (2017) A type I diacylglycerol acyltransferase modulates triacylglycerol biosynthesis and fatty acid composition in the oleaginous microalga Nannochloropsis oceanica. Biotechnology for Biofules, 10: 174

Yang B, Liu J*, Ma X, Guo B, Liu B, Wu T, Jiang Y, Chen F* (2017) Genetic engineering of the Calvin cycle toward enhanced photosynthetic CO2 fixation in microalgae. Biotechnology for Biofules, 10: 229 (Featured article)

Ma X, Yao L, Yang B, Lee Y, Chen F*, Liu J* (2017) RNAi-mediated  silencing of  a pyruvate dehydrogenase kinase enhances triacylglycerol biosynthesis in the oleaginous marine alga Nannochloropsis salina. Scientific Reports, 7: 11485 

Zhou WG*, Wang JH, Chen P, Ji C, Kang Q, Lu B, Li K, Liu J*, Ruan R (2017) Bio-mitigation of carbon dioxide using microalgal systems: advances and Perspectives. Renewable Sustainable Energy Reviews. 76: 1163-1175

Liu J*, Lee Y, Mao X, Li Y* (2017) A simple and reproducible non-radiolabeled in vitro assay for recombinant acyltransferases involved in triacylglycerol biosynthesis. Journal of Applied Phycology, 29: 323-333

2016

Liu J,  Han D, Yoon K, Hu Q, Li Y (2016) Characterization of diacylglycerol acyltransferases in Chlamydomonas reinhardtii: Substrate specificity and their role in triacylglycerol biosynthesis. Plant Journal, 86: 3-19 (Cover, Featured article)

Liu J*, Mao X, Zhou W, Guarnieri M (2016) Simultaneous production of triacylglyerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis. Bioresource Technology, 214: 319-327

Zhang Z, Sun D, Mao X, Liu J*, Chen F* (2016) The crosstalk between astaxanthin, fatty acids and reactive oxygen species in heterotrophic Chlorella zofingiensis. Algal Research,  19: 178-183

Yang B, Liu J*, Jiang Y, Chen F* (2016) Chlorella species as hosts for genetic engineering and expression of recombinant proteins: Progress, challenge and perspective. Biotechnology Journal, 11: 1244-1261 (Cover article)

Guo B, Liu B, Yang B, Sun P,  Lu X, Liu J*,  Chen F* (2016) Screening of diatom strains and characterization of Cyclotella cryptica as a potential fucoxanthin producer. Marine Drugs, 14, 125

Ma X, Chen T, Yang B, Liu J*, Chen F* (2016) Lipid Production from Nannochloropsis. Marine Drugs, 14: 61

Ma X, Liu J*, Liu B, Chen T, Jiang Y, Chen F* (2016) Physiological and biochemical changes reveal stress-associated photosynthetic carbon partitioning into triacylglycerol in the oleaginous marine alga Nannochloropsis oculata. Algal Research16:28-35

2015 

Chen T#, Liu J#, Guo B, Ma X, Sun P, Liu B, Chen F (2015). Light-mediated lipid reduction of Chlorella zofingiensis cultured with glucose through shifting carbon flux from lipid to starch. Scientific Reports, 5:14936

Sun Z, Zhou Z, Gerken H, Chen F, Liu J* (2015) Screening and characterization of oleaginous Chlorella strains and exploration of photoautotrophic Chlorella protothecoides for oil production. Bioresource Technology, 184, 53-62

Edited Book

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Liu J, Sun Z, Gerken H (2016) Recent advances in microalgal biotechnology. Omics Group. ISBN: 978-1-63278-066-9

Invited Book Chapters

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Zhang D*, Zou R, Wang X, Liu J, Mo F (2022) Carbon capture, storage and utilization: a general overview. In: Fu J et al. (Eds). Climate Mitigation and Adaption in China: Policy, Technology and Market. Metallurgical Industry Press, Beijing, pp. 59-105.

Zhang Y, Liu J* (2021) Lipid metabolism and metabolic engineering of eukaryotic microalgae. In:  Advances in Bioenergy. Elsevier. 

Liu J (2018) Batch cultivation for astaxanthin analysis using the green microalga Chlorella zofingiensis under multitrophic growth conditions. In: Barreiro, C., Barredo, J.-L., Eds.), Microbial Carotenoids: Methods and Protocols. Springer New York, New York, NY, pp. 97-106.

Liu J, Chen F (2014). Biology and Industrial Applications of Chlorella: Advances and Prospects. in: Advances in Biochemical Engineering/Biotechnology. Springer Berlin Heidelberg, pp. 1-35. DOI: 10.1007/10_2014_286

Sun Z, Liu J* (2014) Microalgal Biofuels: Oil Biosynthesis, Biotechnology and Applications. In: Govil JN (Ed). Recent Developments in Biotechnology Vol. 3: Microbial Biotechnology. Studium Press LLC.

Liu J, Sun Z, Chen F (2013). Heterotrophic production of algal oils. In: Pandey A, Lee DJ, Chisti Y and Soccol CR (Eds), Algal Biofuels. Elsevier. Pp111-142

Liu J, Hu Q (2013) Chlorella – Industrial Production of Biomass and Chemicals. In: Richmond A and Hu Q (Eds), Handbook of Microalgal Cultures. 2^nd Edition. Wiley Blackwell. pp. 327-338.

Liu J, Huang J, Chen F (2011) Microalgae as Feedstocks for Biodiesel Production. In: Stoytcheva M and Montero G(Eds), Biodiesel-Feedstocks and Processing Technologies. InTech

Wen Z, Liu J, Chen F (2011) Biofuel from Microalgae. In: Murray M-Y (Ed.), Comprehensive Biotechnology-vol 3 Industrial Biotechnology and Commodity Products. 2^nd Edition. Elsevier. pp. 127-133.

Conference Presentations and Posters

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刘进。酰基转移酶在微藻合成生物学中的应用。中国藻业协会微藻分会第七届产学研大会，武汉，2021.4.28-30（邀请报告）

Liu J. 转录因子/调节子调控衣藻中碳/脂质代谢. 20th Algae Symposium of Chinese Society for Oceanology and Limnology（中国海洋湖沼学会藻类学分会第二十次学术讨论会）, Qingdao, China, Nov 25-27, 2019, oral presentation（特邀报告）

Liu J. The Oleaginous Astaxanthin-producing Alga Chromochloris zofingiensis: A Emerging Model for Studying Lipogenesis and Carotenogenesis. The 10th Asia-Pacific Conference on Algal Biotechnology, Nanchang, China, Sep 27-30, 2019, Keynote speaker（大会报告）

Liu J. Epigenetic and transcriptional regulation of carbon/lipid metabolism in Chlamydomonas. 1st Workshop for Cell and Molecular Biology of Chlamydomonas of China（2019年中国首届衣藻分子细胞学术研讨会）, Wuhan, China, May 16-18, 2019, oral presentation（特邀报告）

Liu J. Towards Enrichment of Value-added Products in Algal Lipid Droplets by Targeted Metabolic Engineering. Sino-German 2nd Workshop for Algae Bionergy & Nannochloropsis Synthetic Biology（中德第二届藻类能源与微拟球藻合成生物学双边会议）, Qingdao, China, Nov 26-28, 2018, oral presentation（特邀报告）

Liu J. Chromochloris zofingiensis, an astaxanthin-producing oleaginous alga for studying lipid metabolism and carotenogenesis. The 1^st Sino-British Forum on Algal Biotechnology and Biological Resources（第一届中英藻类生物技术与生物资源双边会议）,Wuhan, China, Sep 18-21, 2018, oral presentation（特邀报告）

Liu J. Algae as Chassis for the Synthesis of Lipids and Value-added Products: How Far Away? 青岛海洋科学与技术国家实验室海洋生物学与生物技术功能实验室2018年度海洋生物学鳌山青年学术论坛，青岛，Feb 2-4, 2018，特邀报告

Liu J. A Histone Demethylase Modulates Carbon Metabolism in Chlamydomonas reinhardtii. 18th International Conference on the Cell and Molecular Biology of Chlamydomonas, Washington DC, USA, Jun 17-21, 2018, presented poster

Liu J. Epigenetic regulation of lipid metabolism in microalgae. 19th Algae Symposium of Chinese Society for Oceanology and Limnology（中国海洋湖沼学会藻类学分会第十九次学术讨论会）, Ningbo, China, Nov 30-Dec 1, 2017, oral presentation（特邀报告）

Liu J. Metabolic engineering of microalgae for enhanced production of value-added products. 2nd Algae Submit of China（中国第二届藻类高峰论坛）, Nanning, China, May 11-12, 2017, oral presentation（特邀报告）

Liu J, Han D, Yoon K, Hu Q, Li Y. Characterization of Chlamydomonas diacylglycerol acyltransferases reveals their distinct substrate specificities and functions in triacylglycerol biosynthesis. 17th International Conference on the Cell and Molecular Biology of Chlamydomonas, Kyoto, Japan, Jun 26-Jul 1, 2016, presented poster 

Liu J, Han D, Yoon K, Hu Q, Li Y. Characterization of Chlamydomonas diacylglycerol acyltransferases reveals their distinct substrate specificities and functions in microalgal triacylglycerol biosynthesis. Bioenergy and Biorefinery Conference – Southeast Asia 2016. Singapore, May 30-June 1, 2016, presented poster

Liu J. Microalgal Triacylglycerol metabolism and epigenetic regulation. 2nd SDIC Microalgae Biotechnology Symposium. Beijing, China, Apr 11-12, oral presentation

Liu J, Yoon K, Han D, Hu Q, Li Y. Substrate specificity and positional preference of Chlamydomonas diacylglycerol acyltransferases critical for stress-related biosynthesis of triacylglycerol. 16th International Conference on the Cell and Molecular Biology of Chlamydomonas, Pacific Grove, CA, USA, Jun 8-13 2014, oral presentation

Liu J, Li Y. Single-tube colony PCR for DNA amplification and transformant screening of microalgae. 7th Annual Algae Biomass Summit, Orland, FL, USA, October 2013, presented poster

Liu J, Chen F. Engineering of An Endogenous Phytoene Desaturase Gene As a Dominant Selectable Marker for Chlamydomonas reinhardtii Transformation and Enhanced Biosynthesis of Carotenoids. 13th AIChe Annual Meeting, San Francisco, CA, USA, November 2013, presented poster

Sun Z, Liu J, Wang M, Chen F. Inhibitory Effects of Microalgal Extracts and Their Active Compounds On Protein Glycation and Glycoxidation. 10th AIChE Annual Meeting, Salt Lake City, UT, USA, November 2010, presented poster

Liu J, Chen F. Astaxanthin production from molasses by Chlorella zofingiensis. 280th Session of the PhD Candidates Forum, Tsinghua University, Shenzhen, China, November 2010, Oral presentation

Liu J, Huang J, Chen F. Genetic engineering for improvement of astaxanthin in microalgae. Global Chinese Health (Functional) Food Symposium, Hong Kong, China, August 2009, presented poster

Liu J, Huang J, Chen F. Metabolic engineering of Chlorella zofingiensis (Chlorophyta) for enhanced biosynthesis of astaxanthin. 34th FEBS Congress: life's Molecular Interactions, Prague, Czech Republic, July 2009, presented poster

Liu J, Huang J, Sandmann G, Chen F. Metabolic engineering for enhanced astaxanthin biosynthesis in Chlorella zofingiensis(chlorophyta). 13th International Biotechnology Symposium and Exhibition, Dalian, China, October 2008, presented poster